2010, ¹ 6





Symmetry of nervous plexuses of human spinal cord and

sympathetic trunk

J. Experimental and Clinical Medicine, 2010, 6, pp.8-13


A. Natishvili Institute of Morphology, Tbilisi, Georgia


A Study of the symmetry and order of the spinal cord nervous trunks has laid a basis for the  belief that the connection of the thoracal nerves with the branchial, lumbar and sacral plexuses displays a tendency of the  human nervous system to develop in the direction of torso sizes reduction and upper extremity lengthening. The similar appears less characteristic of the sympathetic nervous system. However, such tendency is observed in its separate component – stellate ganglions of the branchial plexus i.e. the system has some connection with the human extremities innervation.



Biomechanical principLes of intercostal muscles functional anatomy

J. Experimental and Clinical Medicine, 2010, 6, pp.13-17


Department of Physiological Anatomy, Tbilisi State Medical University, Georgia


A century long dispute on the role of the external and internal intercostal muscles in the process of respiration is still actual. Some of the authors consider them synergists, the others – antagonists.

As the authors of this article  note, the dispute was caused by the fact that all the above-mentioned researches were based on the data of electromyography, according to which both types of muscles during inspiration and expiration showed equally positive impulsation which must be considered a display of reciprocal interaction.

The authors of the article, using a method of the biomechanical analysis, have proved the antagonism of the external and internal intercostal muscles during respiration.



3. NikolaiSvili M., Mchedluri T., Margalitashvili D., Gagolishvili M.

A Study of antioxidaNti PROPERTIES of “Saperavi” grapes oil on rats

J. Experimental and Clinical Medicine, 2010, 6, pp.17-22


I.Gogebashvili State University of Telavi, Georgia


Our researches have shown that oil extracted from the seeds of “Saperavi” grapes which was administered to Vistar rats daily for a week (3 ml of 25% elixir intraperitoneally) increased their survival, and the factor of dose alteration was equal to 1,23.




J. Experimental and Clinical Medicine, 2010, 6, pp.22-25


P.Sarajishvili Institute of Neurology and Neurosurgery; Iv.Javakhishvili Tbilisi State University;

Research Institute of Clinical Medicine


The aim of our study was to perform a hospital-based epidemiological analysis of primary oligodendroglial intracranial tumors in Georgia: the frequency of distribution of this neoplasm and its gender and age aspects. Our data suggest that biological “behaviour” of primary oligodendroglial intracranial tumors has evident relationship with patients’ gender and age.



Morphological Characteristic of Fibroblasts IN Different HistologicalTypes of Colon and Breast Cancer

J. Experimental and Clinical Medicine, 2010, 6, pp.25-28


A. Natishvili Institute of Morphology, Tbilisi, Georgia


The Investigation showed an active process in the stromal elements of malignant tumors. There were determined growth and proliferation in the fibroblasts of malignant tumors. The changes in the stromal elements are supposed to be one of the reasons for malignant tumor spread and growth.



6. NikolaiSvili M., Mchedluri T., MargalitaSHvili D., GagoliSHvili M, Zurabashvili Z.

THE Influence a biologically active compound – grapes oil - on the metabolism of biogenic amines in rat blood

J. Experimental and Clinical Medicine, 2010, 6, pp.28-31


Telavi State University, Georgia


Feeding on grapes oil – a biologically active compound - induces such quantitative distribution of amino acids in rat blood that removes emotional strain in animals, decreases sense of fear, develops and increases attention, memory and cognition, activates the process detoxication, ceases formation of free radicals, supports fat destruction and transfers it in the muscular energy. It stops balding process, takes part in regeneration; in case of contamination reinforces thymus function, also promotes protein formation and procreation.



exfoliative cytology IN diagnosiS OF Basal cell carcinoma

J. Experimental and Clinical Medicine, 2010, 6, pp.31-34


Tbilisi State Medical University; A.Ghvamichava National Centre of  Oncology; Medical Centre of Dermatology-Venerology and Aesthetic Medicine, Tbilisi, Georgia


Basal cell carcinoma is the most common type of malignant non-melanoma skin cancer. It is locally invasive, aggressive and destructive, but has limited capacity to metastasize. Since the proportions of these tumors are heavily pigmented, clinically they may resemble invasive melanoma. The aim of this study was to evaluate the reliability of the cytological method of examination, and comparison of results with  pathomorphologic data and dermatoscopic picture. 98 cases of pigmental basal cell carcinoma were analyzed, and it was proved that exfoliative cytology may become the method of choice as it has high sensitivity and specificity and as well numerous advantages to offer the patient and dermatologist working in an outpatient clinic.




8. Mchedluri T., Metreveli M., Nikolaishvili M.

quantitative evaluation of pesticides in the water, riverside soil, and bottom  sediment of the Alazani river

J. Experimental and Clinical Medicine, 2010, 6, pp.34-38


The State University of Telavi, Georgia


The use of pesticides is one of the most important methods for harvest protection, but they also can bring  negative consequences. Remnants of the pesticides Karate, Decis and DDT were found in the riverside soil, bottom sediment and water of rivers. A chemical research has shown a certain amount of pesticides only in Tsnori and Gurjaani, but there was no DDT in the water of Alazani. In the riverside soil, the quantity of pesticides is high, which can be explained by hot summers and a high content of copper in the soil. Pesticides are abundant in the  villages: Artana, Shakriani, and Tsnori. As for  bottom sediment, a certain quantity of pesticides is found near  Shakriani, Tsnori, and Gurjaani. In the riverside soil and bottom sediment of Alazani are also found some remnants  of DDT.


9. Sikharulidze I, Kordzaia M., Kapanadze N.

Features of the  femalE contracted pelvis

J. Experimental and Clinical Medicine, 2010, 6, pp.38-41


A. Natishvili Institute of Morphology, Tbilisi, Georgia


We have investigated features of the pelvis of Georgian females.  In our study we used the pelvis classification of W. Caldwell and H.Moloy (1933) (they selected four types of the pelvis: gynecoid, android, platipeloid and anthropoid). The characteristics of women’s physical development were estimated by the indices of body length (by R.Martin, 1928) and weight, and women’s constitutional type was determined by the classification of I.Galant (1927). Characteristics of the physical development of newborn children  were also investigated.     

450 practically healthy women at the age of 17-44 were investigated according to the method known as external pelviometry, adopted in obstetric practice. 218 women had the gynecoid type pelvis, 232 women’s pelvis were contracted to different extents. According to the contitutional type: gynecoid pelves were mostly typical of the mesosomic women, and contracted pelves were typical of the women having leptosomic constitution.


10. Basiladze L., Tsalughelashvili A., Chomakhashvili Z.

modern literary data CONCERNING pancreaTIC cancer treatment

J. Experimental and Clinical Medicine, 2010, 6, pp.41-48


A.Ghvamichava National Center of Oncology, Georgia, Tbilisi


The authors have discussed 103 literary sources, the bulk of which was published after 2000. The object of the discussion are data concerning the epidemiology, etiology, clinic, diagnosis of cancer pancreatic and all kinds of cancer treatment. On the basis of their discussion and analysis, the authors consider it documented that the study of pancreatic cancer has to start from the very beginning that is to analyze the results existing at the current stage and implement the ways of their improvement via available methods.