J.EXPERIMENTAL & CLINICAL MEDICINE
2013, ¹ 3
1. GIORGOBIANI M., ZURASHVILI B., SANIKIDZE T., LORDKIPANIDZE T.,
GRDZELISHVILI M., CHALATASHVILI G., GRIGORASHVILI G.
NATIONAL SERVICE CONCEPTION OF SANITARIAN SECURITY AND INSPECTION
J. Experimental and Clinical Medicine, 2013, 3, pp.10-12
TSMU, Department of Preventive Medicine and Environmental Health, Medical Ecological Association, Tbilisi, Georgia
According geopolitical position Georgia is one of the most important countries of the XXI century. Historically it is possible to estimate from different civilizations, but also a variety of political and economic development of the countries with vital interests. Therefore, we considered that it is important to take into account the economical, energetical and environmental development prospects of our country and, therefore, determine priorities, living standards, demographic conditions which will support its fast and efficient development in a short time with it improvement of health indicators. One of the priorities of Georgia sanitation, security and supervision of the National Service.
2. Kverenchkhiladze R., Zurashvili B., Mchedlishvili I.
STATE OF ENVIRONMENTAL HYGIENE IN GEORGIA AND KEY
DIRECTIONS OF ITS IMPROVEMENT
J. Experimental and Clinical Medicine, 2013, 3, pp.13-16
TSMU, Department of Preventive Medicine and Environmental Health;
Department of Public Health. Tbilisi, Georgia
The existing in the country state in the sphere of providing humans with a safe and healthy environment is analyzed. A rather complicated situation, in which the services operating in the sphere of environmental hygiene and health have found themselves during the last 2 decades, is conditioned by many factors. In order to ensure the effective functioning, the employment of different options is recommended for institutional organization of the Environmental Hygiene Service. A mandatory requirement to proper functioning of the institutions responsible for environmental hygiene and public health is the staffing of the existing practical network with specialists of the appropriate qualification (hygiene, epidemiology). Another mandatory requirement for a dramatic improvement of the state of environmental hygiene is the political will of the highest government authorities as a precondition of setting up and functioning of a potent and capable government supervisory service. This will create a solid basis for implementing the constitutionally established fundamental human right to a safe and healthy environment
3. Mchedlishvili I.M., Chochishvili R.M., Mchedlishvili T.I.
Secular trends of Hepatitis B in Georgia
J. Experimental and Clinical Medicine, 2013, 3, pp.17-19
Department of Public Health, TSMU, Tbilisi, Georgia
Was estimated secular trend of Hepatitis B in Georgia for a period of 2001-2012. Study revealed an important increase of the prevalence of chronic hepatitis B. Disease prevalence rate from 2.5 in 2001 had increased to 34,9 per 100 000 in 2008, while distribution of acute hepatitis B during the same period had different tendency: prevalence rate from 8.7 decreased to 0.7 per 100 000 population. Finally distribution of hepatitis B (including chronic forms) in Georgia is much higher than in Europe.
4. Mebonia N., Tsiklauri T., Zhizhilashvili S., Gabrichidze T., Kiknadze K ., Parulava M., Burjanadze I.
Charasteristics of Dhiarea disease with Hemolytic Uremic Sindrome (HUS) among patients hospitalized in M.Iashvili children’s central hospital
J. Experimental and Clinical Medicine, 2013, 3, pp.19-21
Division of Epidemiology and Biostatistics, department of Public Health, TSMU
Introduction. HUS is the polietiologic sindrom, which is mostly secondary complication, and according to the etiologic factors are two types: infection and non-infection. The goal of the study was to estimate epidemiologic characteristics of dhiareas with HUS, and worked out prevention and control measures. Methods. At the children central hospital we carried out active search of dhiarea cases with HUS. To detect possible risk factors was conducted case-control study and for possible risk factors were calculated odds Ratios (OR) and 95% Coffindace interval (95% CI). Results. 17 cases and 34 control persons participated within the study. Among 4 patients (24%) were identificated E.coli, in one case - E.coli and Entamoeba hystolitica together (6%), and proteus mirabilis. According to the study results suspect risk factors were drinking water (OR=2.6, 95%CI = 1.6-11.8) and notwashed fruits (OR=1.4, 95%CI= 0.3 – 6). Conclusions and recommendations. Complications from the HUS are most frequently associated with dhiarea caused by E.coli and are much higher during water transmission. Should be increased population awareness about possible complications of dhiarea diseases and about measures that could be used to avoid such outcomes.
5. Tsimakuridze M., Tsimakuridze M.
Risk Factors and Health Effects in Nitrate Fertilizer Producing Factory
J. Experimental and Clinical Medicine, 2013, 3, pp.22-25
TSMU, Department of Environmental Health and Occupational Medicine, Tbilisi, Georgia
This article is related to the discussion of main characteristics and peculiarities of the risk factors and health effects of the nitrate fertilizer producing plant in Georgia. Therefore these are the main problems in occupational medicine. We believe that foreseeing these factors and thereafter implementing preventive measures would be the best way in achieving greatest results in this direction.
6. Khachapuridze N. A., Tsimakuridze M.P., Zurashvili D.G.,
Tsimakuridze Maia P., Maisuradze E.A.
Causative Factors of Occupational Bronchial Asthma
J. Experimental and Clinical Medicine, 2013, 3, pp.25-29
Department of Environmental and Occupational Health Tbilisi State Medical University, Tbilisi, Georgia
This article is related to the discussion of causative factors of occupational bronchial asthma in industry and agriculture, also between the workers of service field. Therefore the research analysis the importance of evaluating risk factors and implementing preventive measures in the occupational medicine.
7. Zarnadze I., Zarnadze Sh.
Needs of Population in Medical Services and Perspectives of Evaluation
J. Experimental and Clinical Medicine, 2013, 3, pp.29-31
Tbilisi State Medical University, Direction of Health Care Management, Policy and Economy, Tbilisi, Georgia
8. Zarnadze Sh., Zarnadze I.
Global Climate Change and Human Nutrition Adaptation Problem
J. Experimental and Clinical Medicine, 2013, 3, pp.31-33
Tbilisi State Medical University, Direction of Health Care Management, Policy and Economy, Tbilisi, Georgia
9. LOMTADZE L., KITOVANI D.
Global climate change, health and demographic policy, perspectives of development
J. Experimental and Clinical Medicine, 2013, 3, pp.33-35
Department of Environmental and Occupational Health Tbilisi State Medical University, Tbilisi, Georgia
In this article there are discussed items of necessity of ecological altitude in demography, ascertaining role of exogenous and endogenous factors in the structures of diseases and mortality in the population of Georgia, and research of level of ecological pollution on its territory.
10. Darsania T., Kurashvili B., Zarnadze Sh., Zarnadze I.
New Challenges of the Nature and eating behavior
J. Experimental and Clinical Medicine, 2013, 3, pp.35-37
TSMU, Nutritional and age medicine direction, Tbilisi, Georgia
Climate change is recognised as a significant public health issue that will impact on food security. Changes to climate also link with concerns in relation to land degradation, loss of biodiversity, and increases in input demands on the food system which all impact on food security. These consequences on the food system will significantly create long-term impacts for the environment and public health, resulting in decreased food security. The aforesaid problem requires a multidimensional analysis. The aim of our work was to assess the problem. Utilizing method of sociological research, we interviewed 300 people and passing pedestrians. The research showed that Georgian people are not sufficiently informed about contributory factors of global warming as well as are not prepared to participate in the task of its mitigation. It is necessary to upgrade populations awareness about ecology status, its influential factors and active involvement of community in problem solving.
11. Kverenchkhiladze R., Bakradze L., Bezerashvili S., Bakradze T., Sordia G.
The Problem of Ambient Air Hygiene in Georgia by the
Example of a Modern Industrial City
J. Experimental and Clinical Medicine, 2013, 3, pp.37-39
TSMU, Direction of Environment Health and Occupacional Medicine. Tbilisi, Georgia
The state of ambient air of the largest in Georgia industrial center – Tbilisi City has been analyzed and the basic factors conditioning its poor state identified. In addition to the industrial sector of national economy, the share of car and other motor vehicle emissions (exhaust gases) in forming the undesirable ambient air state in Tbilisi is also essential. The downtown districts of Tbilisi have been found particularly affected; in 70% of the air samples taken there increased concentrations of major pollutants are observed. The content of lead in the ambient air of the districts with intensive traffic exceeds the similar data observable in the suburban areas of the city. Correspondingly, the content of lead in the blood of downtown dwellers is much higher as compared with the suburbanites.
The priority directions to address the problem have been set for a short-term, medium-term and long-term period on the basis of a National Environmental Health Action Plan (NEHAP) “Environment and Health”, other legal acts and bylaws. Only through complex, global and intersectoral measures and active interventions on the part of the highest structural units of the state administration the actual results in handling the said problem can be achieved.
12. Vepkhvadze N., Tskhovrebadze N., Tskhovrebadze I., Kiladze N., Kugoti I.
Radioecological Situation of Borjomi-Kharagauli
National Park
J. Experimental and Clinical Medicine, 2013, 3, pp.39-42
TSMU Department of Preventive Medicine and Environmental Health, Tbilisi, Georgia
Radioecological situation of Borjomi-Kharagauli national park and doses of external irradiation of population have been studied. The average annual external irradiation dose of population (without radon component) is 0,66 mSv/y.
Determined, that radiation background and, respectively, doses of external irradiation of the population cannot cause serious adverse effects on the health of population. At the same time, this environmental factor should not be ignored, because combined with various factors of low intensity in nature, the magnitude of the radiation background and total dose of irradiation of the population may contribute to the deteriorating health and development of various anomalies.
13. Vepkhvadze N., Khorbaladze M., Gelovani T., Zurashvili B.,
Kochoradze T.
Prevention of Foodborne Diseases in Georgia
J. Experimental and Clinical Medicine, 2013, 3, pp.42-44
TSMU Department of Preventive Medicine and Environmental Health, Tbilisi, Georgia
The purpose of this research is to study morbidity rate caused by food poisoning in Georgia and development of preventive measures against it.
The results of this study showed that in 2012 there have been significant increases in number of food poisoning, which may be related to the improvements in data collection and registration processes. However, these may be also related to the inadequate food quality control during preparation, storage, transportation and realization stages.
To prevent food poisoning it is necessary to strengthen control on the quality of the food. Especially important is a thorough examination of the imported product, as well as strict control over the preparation, storage, transportation and realization of food.
14. GVINERIA I., JAVAKHADZE R., SAAKADZE V., JURULI M.,
ONIANI T., GVABERIDZE O.
SOME ASPECTS OF IMPACT OF CHEMICAL FACTORS ON THE REPRODUCTIVE
HEALTH OF MAN-WORKERS IN THE JSC “ELECTRIC LOCOMOTIVE”
J. Experimental and Clinical Medicine, 2013, 3, pp.44-47
N. Makhviladze Institute of Labor Medicine and Ecology
Effects of chemical factors on the men-workers reproductive health has been studied in the JSC “Electric Locomotive” by epidemiology study using standard questionnaire. Interviewed contingent exposed to concentration of chemicals (xylene, toluene, benzene, gasoline, lead, copper, manganese compounds, formaldehyde, formalin, acids, and alkali) several times exceeded the MAC in the working air.
The study revealed: majority of chemicals occurred in the plant are known as reproductive-toxics. Man-workers characterized by sexual weakness, their partners had a later pregnancy, spontaneous abortions, trend in the increasing of fetal deaths. There is a high risk of adverse occupational exposure in this plant.
15. JAVAKHADZE R., KHATIASHVILI N., CHIGOGIDZE KH., SHUBLADZE KH., RUKHADZE N.
THE ECOLOGICAL DISEASES
J. Experimental and Clinical Medicine, 2013, 3, pp.47-49
N. Makhviladze Scientific Research Institute of Labor Medicine and Ecology, Tbilisi, Georgia
One of the global actual problems of mankind is ecological problem and as a result of this –people’s health problems, what is the basis of high-grade life of people and state in whole. The mankind fully felt the global crisis, which unambiguously points to anthropogenous toxication of planet. The data of WHO speak about growth of diseases, which are directly depended from ecological situation, there was such concept as ecological diseases. To the most dangerous pollutants of environment belong many organic and nonorganic compounds, which continuous influence causes serious disturbances of main functions of an organism. The main direction of fight against promptly deterioration of environment is a development of criteria of ecological safety and mass introduction of ecologically safe technologies, ensuring global safe and national security through system of efficiency of nature protection of all states of the world community.
16. KVERENCHKHILADZE R., JAVAKHADZE R., CHIKOVANI A., KVATADZE M.,
ARABIDZE M., TATALASHVILI N.
HYGIENIC ASSESSMENT OF AIR CONDITION IN SOME INDUSTRIAL FACILITIES OF CHIATURA ORE-DRESSING AND PROCESSING ENTERPRISE
J. Experimental and Clinical Medicine, 2013, 3, pp.49-51
TSMU, Direction of Environment Health and Occupacional Medicine;
N.Makhviladze Institute of Labour Medicine and Ecology. Tbilisi, Georgia
The works for determination of the concentration of dust and toxic gases in the air of working area of ore-dressing plants and Rgani and Darkveti mines of Chiatura Ore-Dressing and Processing Enterprise and their assessment were performed. The assessment showed the increased concentration which is stipulated by some specific features of technological processes, also it is occurred as a result of application of morally aged and technically obsolete equipments and machines, incorrect organization of working places, inefficiency of some existing ventilation systems in some industrial areas. The working conditions show different degrees of hazardous environment. With the purpose of prevention of unreasonable condition of the air in some industrial facilities there is developed the kit of specific improving measures and consequently delivered to the Administration of the enterprise for its practical implementation.
17. GRDZELISHVILI M. V., LASHKHAURI M. A., GIORGOBIANI M. T., GANUGRAVA I. A.,
KIKNADZE K. G., SHUBITIDZE N. D., MURVANIDZE L. B.
ESTIMATION OF DRINKING WATER QUALITY IN THE KAKHETY REGION ACCORDING TO SALT AND FLUORINE CONTENT
J. Experimental and Clinical Medicine, 2013, 3, pp.52-54
Ltd. G. Natadze Scientific-Research Institute of Sanitary, Hygiene and Medical Ecology
Tbilisi, Georgia
According to the results of seasonal examination of the quality of drinking water in the small- scale water supply systems of 24 villages in Telavi Municipality (124 samples), the waters has favourable organoleptic properties. According to natural salt composition, it mainly has average hardness and optimal mineralization. Increased microbe contamination is not revealed in the most samples. According to fluorine content, the water is physiologically inferior.
18. TUKVADZE SH.
HYGENIC ASSESSMENT OF CONSEQUENT PERIOD OF STOPPAGE OF ZINC FORTIFIED TEA INTAKE
J. Experimental and Clinical Medicine, 2013, 3, pp.54-57
Department of Environmental Health and Occupational Medicine of Tbilisi State Medical University, Georgia
We have studied the ration of the nutrition of the adolescents and conducted its analysis. The research was conducted in the boarding house among the adolescents in which 36 adolescent participated. The results are compared to the norms of physiological requirements of the adolescents taking into account the major substances and energy. Besides that, biochemical monitoring of the Zn requirement in the adolescents has been conducted. Study had revealed Zinc deficiency in 12 boys and 19 girls.. After implementing zinc fortified tea in children’s diet during 90 days show convincing amount of zinc statistics in urine analysis and hair. After 6 months the research was conducted, biochemical analysis was carried out among the children who had distinct symptoms of zinc deficiency (8 adolescents altogether)to check zinc containment in hair and urine. The results showed that zinc containment in hair and urine almost matched the symptoms that initial stage of the observation revealed which confirms the advisability of permanent usage of zinc fortified tea.
19. DARSANIA T., ZARNADZE SH., BIDZISHVILI Z., BAKRADZE T.
PREFERENTIALLY CONSUMED FOODSTUFFS OF GEORGIAN POPULATION AS THE PROGNOSTIC FACTOR IN THE REVISION OF THE EATING BEHAVIOR
J. Experimental and Clinical Medicine, 2013, 3, pp.57-59
TSMU, Nutritional and Age Medicine Direction, Tbilisi, Georgia
Behavior is a crucial factor of health. People in their dietary intake give preference to different products that is not always associated with habits. For studying eating behavior we debriefed Georgian population for revelation of subjective opinions on the following groups: more preferable, less preference and, indifference towards given products. Utilizing a sociological research method, 1450 respondents have been interviewed. Most of the respondents indicated among most preferable products fatty (68,0%) and meat (62,0%) foodstuffs and confectionary (61,0%). The less preferable are vegetables (18,5%). Less number of respondents are indifferent to meat and bread (0,6% and 5,9% correspondingly. Outcome of research revealed factors that influence on eating behavior: sex, psychic condition/state, social status, bodymass, family traditions. A certain role in the formation of preferential eating behavior has family habits. Large-scale interference in the human eating behavior cannot be implemented without big-time policy.
20. Elashvili E.N., Velijanashvili I.G., Imnadze P.G., Gelovani D.O.
Tularemia epizootic in Shida Kartli lowland
J. Experimental and Clinical Medicine, 2013, 3, pp.60-61
Public Health Department of Tbilisi State Medical University; National Center for Disease Control and Public Health, Tbilisi, Georgia
The paper describes Tularemia epizootices innatural zone in Shida Kartli region. There are characterized participant rodents and their ectoparasits spreading in epizootices process of tularemia as well as there is mentioned important role of common vole, house mouse, forest mouse, Ixordae ticks in this preserving epidemic zones.
21. GVISHIANI M.G., TSERETELI M.N., CHKHAIDZE N.N.
THE INFLUENCE OF HARMFUL EFFECTS OF PRODUCTION ENVIRONMENT OF LTD “KASPICEMENT” ON THE UPPER-RESPIRATORY TRACT AND AUDITORY ORGANS OF WORKERS
J. Experimental and Clinical Medicine, 2013, 3, pp.62-63
N.Makhviladze Institute of Labor Medicine and Ecology, Department of Environment and Occupational Medicine, Tbilisi, Georgia
The purpose of this research is the otorhinolaryngological study of 400 workers at LTD “Kaspicement”. The research showed that among the workers of the given group according to nosological forms, be placed first the diseases of upper-respiratory tract, be placed second the diseases of auditory organs. The arrangement of the diseased according to age, work experience and length of service showed that diseases were most common in workers over the age of 50 with substantial work experience. Arrangement of the diseased according to profession showed that the diseases of auditory organ were most common in machinists, locksmiths, drivers and welders.
22. KVERENCHKHILADZE G., BITSADZE N., TEVZADZE K., KANDELAKI T., ABULADZE K.
WATER HYGIENE ON TOPICAL ISSUES
J. Experimental and Clinical Medicine, 2013, 3, pp.64-66
TSMU, Direction of Environment Health and Occupacional Medicine.,Tbilisi, Georgia
The problems of sanitary protection of water objects is well studied in Georgia. The pollution of the main sources is identified. About 67% of total surface water pollution comes on municipal wastewater. The municipal wastewater is the major source of water pollution. It is also important to concentrate over pollution, in the pollution of the water the industrial wastewater is also important. Radical improvement of water resources management requires the implementation of legal regulations as well as long-term (20 year) and short term (5 year) goals and the implementation of appropriate measures.
23. KAJRISHVILI M.A.,KEKELASHILI K.T.
ENVIRONMENT AND A HEALTH PROBLEMS (REVIEW)
J. Experimental and Clinical Medicine, 2013, 3, pp.66-69
Tbilisi State Medical University Department of public Health, Tbilisi, Georgia
For the successful prevention and treatment of diseases the important meaning is assigned to the knowledge of provocative factors. The ecologic risk factors make 20-22% among risk factors influencing human health. Harmful influence of environmental factors on leading contagious and non contagious diseases were revealed. That is why the Ministry of Labor, Health and Social Care together with the Health Care Department and other institutions should take integrated measures of preventive and educational character among population on whole and separate groups as well to protect them from the harmful environmental influence.
24. CHAGANAVA N.
AIR POLLUTION AND CARDIOVASCULAR DISEASES SUMMARY
J. Experimental and Clinical Medicine, 2013, 3, pp.69-70
Department of Medicinal Chemistry, TSMU, Tbilisi, Georgia
In the last decades, research on the causes of cardiovascular disease has made great progress. Heart disease remains the leading cause of death both in Europe and United States. In the past years many studies has focused on the contribution of air pollutants such as O3; CO; SO2; NO2; Particulate Matter (PM) in the onset and/or exacerbation of cardiovascular disease.
25. LEKISHVILI G., ARZIANI B.
QSAR MODELS OF ECOTOXICITY OF SOME ORGANIC COMPOUNDS
J. Experimental and Clinical Medicine, 2013, 3, pp.71-73
Department of Medical Chemistry, Tbilisi State Medical University, Tbilisi, Georgia
A novel molecular descriptor aimed at modeling bioactivity of diverse datasets has been introduced. We demonstrated its efficiency for predictions of toxicity of various organic compounds. The PLS regression was as good as r2=0.97.
26. Hodovanets Y.D., Perizhnyak A.I., Hodovanets A.S.
CARDIOVASCULAR DISEASE IN NEWBORNS: MARKERS OF HYPOXIA
J. Experimental and Clinical Medicine, 2013, 3, pp.73-80
Bukovinian State Medical University, Chernivtsi, Ukraine
The article has results of the study indicators system oxidation and antioxidant protection system of newborn with cardiovascular disorders with history of perinatal pathology. Author shows that there is a need for timely diagnosis of these indices. That will help to diagnose antioxidant insufficiency in hypoxic damage of organism.
27. MANJAVIDZE N., MANJAVIDZE I., CHITAIA G., TZIKLAURI M., ABESADZE M.
STATE OF HEALTH OF REFUGEE CHILDREN FROM ABKHAZIA
J. Experimental and Clinical Medicine, 2013, 3, pp.81-83
TSMU Clinical Skills Center, Department of Pediatrics, Tbilisi, Georgia
There was held an investigation of the health status of 6-15 years old 800 refugee children from Abkhazia. This investigation suggested that 43.5 % of the children had somatic and psycho-emotional dysfunctions. Those having psycho-emotional dysfunctions mostly manifested psycho-neurological dysfunctions too.